Kingston Group: Bioorganic and Natural Products Chemistry

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Experiment in the hood

Kingston’s Laboratory Research

Our lab uses a variety of approaches to develop drugs from natural products.  We collaborate with biologists and microbiologists to discover and develop potential drugs for treatment of cancer, malaria, leishmaniasis, and human African trypanosomiasis (sleeping sickness), and we also work to develop improved methods of drug delivery.

These approaches are illustrated by the projects below.

Antimalarial Natural Product Drug Discovery

Exploring the Merck library of natural products extracts to find and study potential new antimalarial agents.

Anticancer Natural Products Drug Discovery

Using novel bioassay to discover inhibitors of the proteasome

Drug Delivery

Using gold nanoparticles to deliver anticancer drugs directly to the tumor site. 

Virginia Drug Discovery Consortium

The Virginia Drug Discovery Consortium (VaDDC) has a threefold mission:

To promote the growth and advancement of drug discovery and development programs at universities and research institutes within Virginia, particularly through inter-institutional collaboration.

To help the pharmaceutical industry bring life-saving and quality of life solutions to patients through innovative collaborations with Virginia’s best and brightest researchers.

To promote and enhance the attractiveness of Virginia as an environment for pharmaceutical and biotech companies.